Evidence supporting the use of: Curcumin
For the health condition: Canker Sores

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Curcumin, the primary active component of turmeric (Curcuma longa), has been increasingly studied for its potential role in supporting or treating canker sores (aphthous ulcers). The evidence supporting its use is primarily scientific, with several small-scale clinical trials and in vitro studies indicating beneficial effects. Curcumin exhibits potent anti-inflammatory, antioxidant, and antimicrobial properties, all of which are relevant to the pathophysiology of canker sores, which involve local inflammation and tissue damage.

A number of randomized controlled trials (RCTs), mostly conducted in India and Iran, have evaluated curcumin gel or mouthwash in the management of minor aphthous ulcers. These studies generally report that topical curcumin can significantly reduce pain, erythema, and ulcer size compared to placebo, and in some cases, its efficacy is comparable to standard treatments like corticosteroid gels. For example, a 2014 double-blind study published in the Journal of Oral Pathology & Medicine found that a 2% curcumin gel was as effective as triamcinolone acetonide in decreasing ulcer severity and pain over 7 days.

It should be noted, however, that while these results are promising, most studies are small, and larger, well-designed clinical trials are needed to confirm efficacy and safety. Nonetheless, current scientific evidence supports the potential use of topical curcumin as an adjunct or alternative treatment for canker sores, particularly for individuals seeking non-steroidal options.

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Other ingredients used for Canker Sores

aloe vera
bamboo
basil
myrobalan
betel
bisabolol
blackberry
bасора
chamomile
clove
coating
coconut milk
Coptis chinensis
curcumin
dog rose
folate
ginger
horseradish
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
magnesium
milk
mustard seed
spruce
omega-3 fatty acids
oregano
oregon grape
parsley
peppermint oil
pineapple
plantain
rhizome
sage
schizonepeta
scrophularia root
slippery elm bark
sphaeranthus indicus
thyme
triphala
vitamin B12
vitamin C
zinc
yellow root
squawvine
chickweed
typhonium
xanthium (cockleburs)
papaya
neem tree
nut grass
clerodendrum indicum
ferula assafoetida
commiphora
blackboard tree
boxthorne
buckthorn
lemongrass
myrrh
siler root
hyacinth bean
morinda
oriental arborvitae
trichosanthes
zanthoxylum
sheep's sorrel
eucalyptus
menthol oil
aster root
paw paw
herbal blend (proprietary)
indigo leaves
Ash
Avens
Agastache
Ardisia
acacia
Agrimony
Achyranthes
Anamu
American Liverleaf
Agrimonia pilosa
Asteracea
Acemannan
Amor seco
Arisaema
Bee Propolis
Bermuda Grass
Blue Flag
Bai Ji
Baphicacanthus cusia
Bidens pilosa
Blackthorn
Bicarbonate
Balsam
Bishop's Weed
Bayleaf
Black galingale
Barleria
Bitter Grass
Bloodroot
Banyan
Bee products
Black Nightshade
Bombax
Borassus aethiopum
Bacteria
Bassia scoparia
Borneol
Coconut
Curry leaf
Calendula
Clerodendrum trichotomum
Chlorophyllin
Carvacrol
Capillary Artemisia
Citron
Capsaicin
Cajuput
Chinese Raisintree
Cowherb
Centipeda
Cistus
Corktree
Collinsonia
Copaiba Oil
Celosia
Chrysophanics
Dianthus
DIVI-DIVI
Dragonhead
David's Milkberry
European Elder
Eclipta
Embelia
Galangal
Little ironweed
Mustard
Mallow
Rose
Snakeroot (unspecified)
Sandalwood
Sumac