Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Centipeda, particularly Centipeda minima, is a herb used in traditional Chinese medicine and some other ethnomedical systems. Its use for oral conditions, including canker sores (aphthous ulcers), is primarily based on traditional practice rather than robust scientific evidence. In traditional Chinese medicine, Centipeda is believed to have anti-inflammatory, antimicrobial, and wound-healing properties, which are thought to be beneficial for various inflammatory conditions, including those affecting the oral mucosa. Traditional preparations may include mouth rinses, topical pastes, or inclusion in multi-herb formulas for oral ulcers.

However, scientific validation for its efficacy specifically against canker sores is limited. Some laboratory studies have identified anti-inflammatory and antimicrobial compounds in Centipeda minima, such as sesquiterpene lactones, which could theoretically be beneficial for oral ulcer healing. Yet, there are no high-quality clinical trials or systematic reviews that confirm its effectiveness for canker sores in humans. The evidence thus remains primarily anecdotal and based on traditional use, with only preliminary mechanistic support from laboratory and animal research.

In summary, the use of Centipeda for canker sores is justified by tradition, with a modest level of preliminary scientific plausibility, but lacking direct clinical evidence.

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