Evidence supporting the use of: Aloe
For the health condition: Canker Sores

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Aloe vera is commonly used to support the healing of canker sores (aphthous ulcers), and there is some scientific evidence to support its topical application for this purpose. A number of clinical studies have evaluated the effect of Aloe vera gel on oral ulcers. For example, a randomized, double-blind, placebo-controlled trial published in 2012 in the journal Dental Research Journal found that topical application of Aloe vera gel significantly reduced the size and pain of aphthous ulcers compared to placebo. Similarly, another study published in Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology (2010) showed faster healing and pain reduction with Aloe vera compared to standard treatments.

The proposed mechanisms of action include anti-inflammatory properties, promotion of wound healing, and antimicrobial effects, all relevant to the healing of oral mucosal lesions. Aloe vera gel contains compounds such as acemannan, which has been shown to accelerate tissue repair and reduce inflammation. While these findings are promising, most studies to date have been small and sometimes limited by methodological weaknesses.

In summary, the use of Aloe vera for canker sores is supported by several clinical trials and is consistent with its traditional use for wound healing and inflammation. However, larger and higher-quality studies are needed to establish its efficacy definitively. The current evidence base rates as moderate.

More about Aloe
More about Canker Sores

Other ingredients used for Canker Sores

aloe vera
bamboo
basil
myrobalan
betel
bisabolol
blackberry
bасора
chamomile
clove
coating
coconut milk
Coptis chinensis
curcumin
dog rose
folate
ginger
horseradish
lactobacillus reuteri
lactobacillus salivarius
lactoperoxidase
lemon
licorice root
magnesium
milk
mustard seed
spruce
omega-3 fatty acids
oregano
oregon grape
parsley
peppermint oil
pineapple
plantain
rhizome
sage
schizonepeta
scrophularia root
slippery elm bark
sphaeranthus indicus
thyme
triphala
vitamin B12
vitamin C
zinc
yellow root
squawvine
chickweed
typhonium
xanthium (cockleburs)
papaya
neem tree
nut grass
clerodendrum indicum
ferula assafoetida
commiphora
blackboard tree
boxthorne
buckthorn
lemongrass
myrrh
siler root
hyacinth bean
morinda
oriental arborvitae
trichosanthes
zanthoxylum
sheep's sorrel
eucalyptus
menthol oil
aster root
paw paw
herbal blend (proprietary)
indigo leaves
Ash
Avens
Agastache
Ardisia
acacia
Agrimony
Achyranthes
Anamu
American Liverleaf
Agrimonia pilosa
Asteracea
Acemannan
Amor seco
Arisaema
Bee Propolis
Bermuda Grass
Blue Flag
Bai Ji
Baphicacanthus cusia
Bidens pilosa
Blackthorn
Bicarbonate
Balsam
Bishop's Weed
Bayleaf
Black galingale
Barleria
Bitter Grass
Bloodroot
Banyan
Bee products
Black Nightshade
Bombax
Borassus aethiopum
Bacteria
Bassia scoparia
Borneol
Coconut
Curry leaf
Calendula
Clerodendrum trichotomum
Chlorophyllin
Carvacrol
Capillary Artemisia
Citron
Capsaicin
Cajuput
Chinese Raisintree
Cowherb
Centipeda
Cistus
Corktree
Collinsonia
Copaiba Oil
Celosia
Chrysophanics
Dianthus
DIVI-DIVI
Dragonhead
David's Milkberry
European Elder
Eupolyphaga sinensis
Eclipta
Essential Oil Blend
Euphorbia
European-Five Finger Grass
Embelia
Eugenol
Flueggea suffruticosa
Fuchsia
Fang-Feng
Ficus simplicissima
Frankincense
Gnaphalium
Glycolic acid
Giant Blazingstar
Glechoma hederacea
Gallotannin
Galangal
Little ironweed
Mustard
Mallow
Oak
Rose
Snakeroot (unspecified)
Sandalwood
Sumac

Products containing Aloe

We currently have no products on Caring Sunshine that contain this ingredient.