Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin, a flavonoid glycoside found in many fruits and vegetables (notably in buckwheat, citrus fruits, and apples), has garnered scientific interest for its potential anticancer properties. Laboratory and animal studies have demonstrated that rutin exhibits antioxidant, anti-inflammatory, and anti-proliferative effects, which may contribute to cancer prevention or supportive care. In vitro studies suggest that rutin can induce apoptosis (programmed cell death) in several types of cancer cells, inhibit angiogenesis (formation of new blood vessels that tumors need to grow), and modulate signaling pathways related to cancer progression. Some animal studies have shown that rutin administration can reduce tumor growth and metastasis, likely due to its capacity to scavenge free radicals and modulate immune function.

However, despite these promising preclinical findings, robust human clinical trials demonstrating rutin’s efficacy in cancer prevention or treatment are lacking. Most available human data are limited to observational or small pilot studies, which are insufficient to draw definitive conclusions. Thus, while there is a scientific rationale and some preliminary evidence for rutin’s potential anticancer effects, the current level of evidence is moderate at best and does not support its use as a standalone or primary therapy for cancer prevention. Rutin may be best considered as a dietary component within a balanced, plant-rich diet, rather than a proven supplement for cancer prevention.

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Products containing rutin

Nature's Sunshine Mega-Chel
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Vari-Gone
Nature's Sunshine B-Complex
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C Ascorbates
Nature's Sunshine Citrus Bioflavonoids (Vitamin C)