Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Curcumin, the principal bioactive compound in turmeric (Curcuma longa), has been traditionally used in Ayurvedic and Chinese medicine for its anti-inflammatory and antioxidant properties. In the context of cancer prevention, there is a growing body of scientific evidence from in vitro (cell culture) and in vivo (animal) studies demonstrating curcumin’s potential anti-cancer effects. These studies have shown that curcumin can modulate multiple cell signaling pathways involved in the development and progression of cancer, including pathways related to cell proliferation, apoptosis (programmed cell death), angiogenesis (formation of new blood vessels), and metastasis.

Some early-phase human clinical trials suggest that curcumin supplementation is safe and may help decrease levels of certain biomarkers associated with cancer risk or inflammation. However, the clinical evidence supporting curcumin’s effectiveness in preventing or treating cancer in humans is still limited and inconclusive. Issues such as poor bioavailability, variability in formulations, and lack of large-scale, well-controlled trials prevent higher evidence grades.

While preclinical studies are promising and support the plausibility of curcumin’s anti-cancer activity, definitive evidence from human studies is lacking. Thus, curcumin is considered a scientifically plausible adjunct for cancer prevention, but it should not replace conventional cancer prevention or treatment strategies. Further research is needed to clarify its role, optimal dosage, and long-term safety in cancer prevention.

More about curcumin
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Other ingredients used for Cancer (prevention)

Other health conditions supported by curcumin

Products containing curcumin

Nature's Sunshine Turmeric Curcumin (Formerly CurcuminBP)