Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Centella asiatica has a history of use in traditional medicine for wound healing, including burns and scalds, but its application is also supported by emerging scientific evidence. Several in vitro and in vivo studies have demonstrated that extracts of Centella asiatica, particularly its triterpenoid compounds such as asiaticoside and madecassoside, can enhance wound healing by promoting collagen synthesis, stimulating fibroblast proliferation, and exhibiting anti-inflammatory and antioxidant activities. Animal studies have shown that topical application of Centella asiatica extracts can accelerate healing and reduce scarring in burn wounds. A small number of human clinical studies and case series also suggest benefit, though many have limitations such as small sample sizes and lack of rigorous controls. Reviews and meta-analyses acknowledge the potential of Centella asiatica in supporting the healing of burns and scalds, but consistently call for larger, high-quality randomized controlled trials to confirm efficacy and establish standardized dosing and formulations. In summary, while evidence is not definitive, there is a moderate scientific basis for using Centella asiatica to support the treatment of burns and scalds, supplementing its traditional use for this purpose.

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