Amino acid blends or complexes are used to support the recovery from burns and scalds because significant scientific evidence indicates that severe burns dramatically increase the body's metabolic demands and protein breakdown. Burn injuries cause substantial loss of proteins through exudation, increased catabolism, and impaired synthesis, leading to muscle wasting and impaired wound healing if not addressed. Supplementing with amino acids—particularly essential amino acids—can help to mitigate these effects by providing the necessary building blocks for protein synthesis, immune function, and tissue repair.

Clinical studies have shown that enteral or parenteral nutrition enriched with amino acids (such as glutamine, arginine, and branched-chain amino acids) improves nitrogen balance, supports immune response, and accelerates wound healing in burn patients. Guidelines from organizations such as the American Burn Association and ESPEN (European Society for Clinical Nutrition and Metabolism) recommend increased protein and amino acid intake for burn patients, often specifying 1.5–2 g/kg/day of protein or amino acids. Some large randomized controlled trials and meta-analyses support the use of specific amino acids, such as glutamine, to reduce infection rates and hospital stay, although not all findings are universally positive.

In summary, there is a scientific rationale and clinical evidence for using amino acid blends or complexes to support recovery from burns and scalds, though the precise formulation and benefits can vary by patient and severity.