Bioflavonoids (mixed), a group of plant-derived compounds also known as flavonoids, have a long history of traditional use in herbal medicine for various respiratory ailments, including bronchitis. Historically, they have been used because of their perceived ability to strengthen capillaries, reduce inflammation, and support immune function. Some traditional remedies for bronchitis have included foods and herbs rich in bioflavonoids, such as citrus fruits, elderberry, and rutin-containing plants.

However, scientific validation for the efficacy of bioflavonoids in treating or supporting bronchitis specifically is limited. While there is some evidence that certain bioflavonoids possess antioxidant and mild anti-inflammatory properties, clinical studies directly examining their effect on bronchitis symptoms or outcomes are lacking. Most of the available research focuses on their general antioxidant activity rather than direct benefits in respiratory diseases. Thus, the use of mixed bioflavonoids for bronchitis is primarily justified by their traditional use rather than robust scientific evidence.

In summary, while bioflavonoids have been used in traditional medicine for bronchitis, there is little high-quality scientific evidence to support their efficacy in this specific condition. Their use is best viewed as a complementary approach based on tradition, not a proven therapy.