Arani (Premna integrifolia), also known as "Agnimantha" in Ayurveda, is a plant traditionally used in Indian medicine for various inflammatory and infectious conditions, including boils. The use of Arani for boils is primarily rooted in traditional Ayurvedic practices, where it is believed to possess anti-inflammatory, antimicrobial, and wound-healing properties. Classical texts often describe preparations of Arani bark or leaves, sometimes as poultices, for topical application on skin eruptions and abscesses, including boils.

However, direct modern scientific studies specifically evaluating the efficacy of Arani for the treatment of boils are limited. Some laboratory studies have suggested that extracts of Premna integrifolia demonstrate antimicrobial activity against certain bacteria, which could theoretically support its use for infectious skin conditions. Additionally, its anti-inflammatory and antioxidant activities, as evidenced in some in vitro and animal studies, may contribute to symptomatic relief in inflammatory lesions like boils.

Despite these findings, the evidence is not robust or specific enough to confirm its effectiveness for boils in clinical settings. Most of the support for its use remains in the realm of tradition and anecdotal observation rather than rigorous clinical validation. Therefore, while Arani continues to be used in traditional medicine for boils, high-quality scientific evidence for this particular indication remains lacking.