Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sagebrush, which commonly refers to species in the genus Artemisia (such as Artemisia tridentata), has a long history of use in traditional Indigenous medicine in North America. Ethnobotanical records indicate that various Native American tribes utilized sagebrush leaves and preparations for treating bites and stings from insects, spiders, and occasionally snakes. These uses often involved applying crushed or chewed leaves directly to the affected area or creating poultices and washes. The rationale for use was typically based on observed anti-inflammatory or soothing effects, and sagebrush was valued for its aromatic and potentially antimicrobial properties.

However, scientific validation for these uses is limited. Some laboratory studies have identified antimicrobial and anti-inflammatory compounds in Artemisia species, such as terpenoids and flavonoids, but there is a lack of direct clinical or preclinical studies focused on bites and stings. The traditional rating of 2 reflects that while the practice is well-documented ethnographically, robust scientific evidence is lacking, and most support comes from oral histories and ethnobotanical surveys rather than controlled studies.

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