Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Prickly Ash (commonly referring to species in the Zanthoxylum genus) has a history of use in North American indigenous and traditional herbal medicine, including for bites and stings. Historically, various Native American tribes used preparations from Prickly Ash bark or berries topically on the skin to relieve pain, swelling, and irritation from insect bites and stings. The plant was thought to have counterirritant and mild analgesic properties, and it was sometimes included in poultices or washes for this purpose. However, despite this traditional use, there is little to no modern scientific research directly evaluating the efficacy or safety of Prickly Ash for treating bites and stings. Most contemporary herbal references mention the historical use but do not cite clinical or laboratory studies supporting its effectiveness for this indication. Thus, the evidence supporting Prickly Ash for bites and stings is primarily traditional, with a low level of supporting documentation.

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