Evidence supporting the use of: Menthol
For the health condition: Bites and Stings
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Menthol is included in topical preparations for bites and stings primarily due to its scientifically recognized action as a counterirritant and its ability to provide a cooling sensation when applied to the skin. This cooling effect is mediated through the activation of the TRPM8 receptor, which is responsible for the sensation of cold. The soothing, cooling sensation produced by menthol can temporarily distract from itching, discomfort, or mild pain caused by insect bites or stings. Several over-the-counter products for insect bites and minor skin irritations contain menthol for this reason.
However, while the physiological mechanism of menthol’s action is well-understood and there is clinical evidence supporting its role in itch and mild pain relief, the direct evidence specifically for bites and stings is limited. Most support for its use in this context is extrapolated from studies on pruritus (itch) and minor skin irritations rather than large, high-quality trials focused solely on insect bites or stings. Thus, the evidence rating is moderate, reflecting a plausible mechanism and common use, but a lack of extensive, condition-specific clinical trials.
In summary, menthol's use for bites and stings is scientifically plausible and widely accepted in over-the-counter remedies, but the direct, high-quality evidence base specifically for these conditions is not robust.
Other ingredients used for Bites and Stings
aloe verabasil
beta caryophyllene
beta-pinene
betel
bisabolol
black cumin
black walnut
bасора
chamomile
citrus oil
turmeric
curcumin
echinacea purpurea
goldenseal
green tea
hemp oil
horseradish
honeysuckle
lavender
mustard seed
oregano
phenolic acids
plantain
rosemary
sage
schizonepeta
sphaeranthus indicus
thyme
vitamin C
vitamin E
zinc
bentonite
chickweed
xanthium (cockleburs)
papaya
shen-chu
mugwort
neem tree
nut grass
clerodendrum indicum
paederia foetida
blackboard tree
boxthorne
buckthorn
lemongrass
siler root
fern
zanthoxylum
eucalyptus
wintergreen
camphor oil
menthol oil
paw paw
herbal blend (proprietary)
melaleuca alternifolia
geranium
arnica
Ash
Avens
Asclepias cordifolia
Angel's Trumpet
Ardisia
Angelica
Achyranthes
Anamu
Abrus
Alchornea
Aconite
Adrenergic amines
American Liverleaf
Aquilegia formosa
Alsonia scholaris
Asteracea
Abuta
Amor seco
Arani
Arisaema
Bee Propolis
Babchi
Baphicacanthus cusia
Bidens pilosa
Black-Eyed Susan
Balsam
Bishop's Weed
Barleria
Bitter Grass
Brazillian peppertree
Bisabolene
Baccharoides anthelmintica
Bee products
Black Nightshade
Black root
Borneol
Calendula
Calotropis gigantea
Colloidal Silver
Capillary Artemisia
Cinquefoil
Cajuput
Chinese Raisintree
Cowherb
Curcumen
Cedar
Centipeda
Castile Soap
Cocklebur
Copaiba Oil
Citronella
Devil's Club
Dichrostachys glomerata
European Elder
Erodium cicutarium
Eclipta
Echinacea
Emu Oil
Essential Oil Blend
Eupatorium
Euphorbia
Eugenol
Mustard
Spikenard
Vervain
Other health conditions supported by Menthol
Abdominal PainAllergies (respiratory)
Athletic and Exercise Aids
Backache
Bites and Stings
Bronchitis
Canker Sores
Colds (decongestant)
Colds (general)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Cough (dry)
Cough (general)
Cough (spastic)
Dermatitis
Digestion (poor)
Eczema
Exercise