Evidence supporting the use of: Menthol
For the health condition: Bites and Stings

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Menthol is included in topical preparations for bites and stings primarily due to its scientifically recognized action as a counterirritant and its ability to provide a cooling sensation when applied to the skin. This cooling effect is mediated through the activation of the TRPM8 receptor, which is responsible for the sensation of cold. The soothing, cooling sensation produced by menthol can temporarily distract from itching, discomfort, or mild pain caused by insect bites or stings. Several over-the-counter products for insect bites and minor skin irritations contain menthol for this reason.

However, while the physiological mechanism of menthol’s action is well-understood and there is clinical evidence supporting its role in itch and mild pain relief, the direct evidence specifically for bites and stings is limited. Most support for its use in this context is extrapolated from studies on pruritus (itch) and minor skin irritations rather than large, high-quality trials focused solely on insect bites or stings. Thus, the evidence rating is moderate, reflecting a plausible mechanism and common use, but a lack of extensive, condition-specific clinical trials.

In summary, menthol's use for bites and stings is scientifically plausible and widely accepted in over-the-counter remedies, but the direct, high-quality evidence base specifically for these conditions is not robust.

More about Menthol
More about Bites and Stings

Products containing Menthol

We currently have no products on Caring Sunshine that contain this ingredient.