Evidence supporting the use of: Mahonia (unspecified)
For the health condition: Bites and Stings

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Mahonia species, such as Mahonia aquifolium (Oregon grape), have a history of traditional use by Indigenous peoples and herbalists for various skin conditions, including bites and stings. These uses are primarily based on empirical, folkloric knowledge rather than rigorous scientific evaluation. In traditional medicine, Mahonia root and bark preparations have been applied topically to relieve irritation, inflammation, and infection caused by insect bites and stings. The rationale often cited is the plant’s antimicrobial and anti-inflammatory properties, attributed mainly to the alkaloid berberine found in Mahonia species. However, while berberine has demonstrated antimicrobial activity in laboratory settings, there is minimal direct scientific research specifically evaluating Mahonia’s effectiveness for treating bites and stings in humans. No clinical trials or controlled studies substantiate its use for this indication. Therefore, although Mahonia is traditionally used for various skin ailments and has plausible pharmacological effects, its application for bites and stings is supported by tradition rather than scientific validation.

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