Laggera pterodonta is traditionally used in various African and Asian ethnomedicinal systems for the treatment of bites and stings, such as those from insects and snakes. Historical records and ethnobotanical surveys document the application of its leaves, either as poultices or topical preparations, by local healers and communities. The rationale for its use is primarily based on anecdotal evidence and longstanding traditional knowledge, which attribute anti-inflammatory, analgesic, and possibly antitoxic properties to the plant.

Scientific studies on Laggera pterodonta have identified the presence of bioactive compounds such as sesquiterpenes, flavonoids, and essential oils, some of which have demonstrated anti-inflammatory and antimicrobial activities in laboratory settings. However, there is a lack of direct clinical or robust preclinical studies specifically examining its efficacy against the toxins or symptoms resulting from bites and stings. Most of the contemporary support for this use is thus derived from traditional practice rather than formal pharmacological validation.

In summary, while Laggera pterodonta is widely used in folk medicine for bites and stings, the evidence supporting its efficacy is largely traditional, with limited scientific substantiation to date.