Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Achyranthes species, particularly Achyranthes aspera, have a longstanding history of use in traditional medicine systems such as Ayurveda and folk medicine for the treatment of bites and stings, including those from snakes, insects, and scorpions. The roots, leaves, and seeds have been employed in various preparations, either topically or orally, to reduce the toxicity, inflammation, and pain associated with venomous bites. This traditional use is documented in several ethnobotanical surveys and Ayurvedic texts, which describe Achyranthes as an ingredient in antidote formulations and as an anti-inflammatory agent.

Despite this traditional backing, scientific validation is limited. A small number of in vitro and animal studies have explored the antivenom and anti-inflammatory properties of Achyranthes extracts, showing some degree of inhibition of edema and cytotoxic effects induced by venom. However, these studies are preliminary, not standardized, and do not provide conclusive evidence for clinical efficacy in humans. No high-quality clinical trials or robust pharmacological evaluations have confirmed its effectiveness for treating bites and stings. Thus, the current evidence base is primarily traditional, with a low to moderate rating due to the lack of rigorous scientific support.

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