Evidence supporting the use of: Magnesium
For the health condition: Bipolar Mood Disorder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Magnesium has been investigated for its potential role in supporting or treating Bipolar Mood Disorder (BMD), although the scientific evidence remains limited and somewhat inconclusive. Magnesium is an essential mineral involved in many neurochemical processes, including the regulation of neurotransmitters and modulation of the hypothalamic-pituitary-adrenal (HPA) axis, both of which may be relevant in mood disorders such as bipolar disorder. Some studies have suggested that individuals with mood disorders, including bipolar disorder, may have lower serum magnesium levels compared to healthy controls. Small-scale clinical trials and case reports have indicated that magnesium supplementation, often as an adjunct to conventional mood stabilizers, might help reduce symptoms of mania or rapid cycling in bipolar disorder. For instance, a few randomized controlled trials have observed improvements in mood stability and a reduction in manic symptoms when magnesium is added to standard therapy. However, these studies generally suffer from small sample sizes, methodological limitations, and inconsistent findings.

Major psychiatric guidelines do not currently recommend magnesium as a standalone or primary treatment for bipolar disorder, and it is not considered a substitute for established mood stabilizers like lithium or valproate. The evidence base is considered preliminary, and larger, well-designed studies are needed to determine efficacy and safety. In summary, while there is some scientific rationale and early clinical data to support magnesium supplementation as an adjunct therapy in BMD, the overall strength of evidence remains modest, meriting a rating of 2 out of 5.

More about magnesium
More about Bipolar Mood Disorder

Other health conditions supported by magnesium

Abdominal Pain
Abscesses
Acid Indigestion
Addictions (drugs)
Addictions (general remedies for)
Adrenal Fatigue
Aging (prevention)
Alcoholism
Alkalosis
Allergies (respiratory)
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Control (countering side effects)
Body Building
Body Odor
Boils
Broken Bones
Bronchitis
Bulimia
Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Cholesterol (high)
Circulation (poor)
Colon (atonic)
Constipation (adults)
Convulsions
Cramps (leg)
Cramps (menstrual)
Cramps and Spasms
Depression
Diabetes
Digestion (poor)
Dizziness
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Exercise
Fatigue
Fibromyalgia Syndrome
Gastritis
Headache (cluster)
Headache (general)
Headache (tension)
Hearing Loss
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Insomnia
Mental Illness
Migraine
Mood Swings
Muscle Tone (lack of)
Nerve Damage
Nervous Exhaustion
Nervousness
Neurosis
Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
Senility
Shock
Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
Sugar Cravings
Surgery (healing from)
Surgery (preparation for)
Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores

Products containing magnesium

Nature's Sunshine CleanStart Mild
Nature's Sunshine Adrenal Support
Nature's Sunshine AIVIA Hydrate
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AnxiousLess
Nature's Sunshine AnxiousLess
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Calcium Plus Vitamin D
Nature's Sunshine Cellular Energy
Nature's Sunshine Chromium-GTF
Nature's Sunshine Coral Calcium
Nature's Sunshine Coral Calcium
Nature's Sunshine Fibralgia
Nature's Sunshine Free Amino Acids
Nature's Sunshine Gentle Move
Nature's Sunshine Glandular System
Nature's Sunshine Heavy Metal Detox
Nature's Sunshine Magnesium
Nature's Sunshine Magnesium Complex
Nature's Sunshine Mega-Chel
Nature's Sunshine Mind-Max
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Power Beets Pouch
Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Sea Calcium (Nature's)
Nature's Sunshine Sunshine Heroes Whole Food Papayazyme
Nature's Sunshine Silver Shield BioGuard Hand & Body Cream
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Urinary Maintenance
Nature's Sunshine Urinary System
Nature's Sunshine VitaWave