Evidence supporting the use of: Nettle
For the health condition: Benign Prostate Hyperplasia

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Nettle (Urtica dioica) root has been used both traditionally and in modern phytotherapy to support urinary health, particularly in men with Benign Prostate Hyperplasia (BPH). Scientifically, several clinical studies and reviews have investigated the efficacy of nettle root extract in alleviating lower urinary tract symptoms (LUTS) associated with BPH. The proposed mechanisms include inhibition of sex hormone-binding globulin, modulation of inflammatory pathways, and interference with enzymes involved in prostate cell growth (such as 5-alpha-reductase). Randomized, placebo-controlled trials (e.g., Safarinejad, 2005; Lichius & Muth, 1997) have shown statistically significant improvements in urinary flow, nocturia, and symptom scores compared to placebo. Nettle root is often used in combination with other botanicals, such as saw palmetto, in commercial formulations, and European guidelines sometimes include nettle root as an option for mild-to-moderate BPH symptoms. However, while there is scientific validation for its use, the overall strength and consistency of the evidence is moderate—most studies are small, of short duration, and sometimes industry-sponsored. Therefore, nettle root cannot be considered a primary treatment but may be a supportive, adjunctive therapy for BPH. Further large-scale, independent trials are needed to clarify its benefits and mechanisms.

More about Nettle
More about Benign Prostate Hyperplasia