Evidence supporting the use of: Fish oil
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Fish oil, rich in omega-3 fatty acids (EPA and DHA), has substantial scientific evidence supporting its use for arterial and cardiovascular health. Multiple randomized controlled trials and meta-analyses have demonstrated that omega-3s can help reduce triglyceride levels, lower blood pressure modestly, and exert anti-inflammatory effects that may benefit arterial function. Omega-3s are also associated with reduced platelet aggregation, which can lower the risk of arterial blockages. The American Heart Association and other reputable organizations recommend fish oil supplementation or increased fish consumption for individuals at risk of cardiovascular disease, although the strength of recommendations may vary based on individual risk profiles and the specific cardiovascular outcomes considered.

However, recent large trials have produced mixed results regarding fish oil’s ability to reduce major cardiovascular events (like heart attack or stroke) in the general population. Some benefits appear more pronounced in those with elevated triglycerides or existing heart disease. Importantly, fish oil does not replace standard therapies such as statins for cholesterol management. Overall, there is robust scientific validation that fish oil supports arterial health, particularly for lowering triglycerides and contributing to a healthy lipid profile, but its effect on major cardiovascular outcomes is still being refined by ongoing research.

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