Evidence supporting the use of: Lavender
For the health condition: Anxiety Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Lavender (Lavandula angustifolia) has been traditionally used for its calming and anxiolytic effects, but recent scientific research also supports its use in the management of anxiety disorders. Several randomized controlled trials (RCTs) and systematic reviews have evaluated the efficacy of lavender oil, particularly in the form of oral supplements (e.g., Silexan), for reducing symptoms of generalized anxiety disorder (GAD) and subsyndromal anxiety. Meta-analyses indicate that lavender oil can significantly reduce anxiety symptoms compared to placebo, with efficacy comparable to some standard anxiolytics but with a more favorable side effect profile.

The proposed mechanisms involve modulation of neurotransmitter systems, particularly by interacting with voltage-dependent calcium channels and inhibiting serotonin reuptake, which may contribute to its anxiolytic properties. Inhalation of lavender essential oil has also been studied, with some trials showing acute reductions in anxiety in clinical and dental settings. However, oral administration appears to have the strongest evidence base.

Guidelines from some European medical authorities recognize oral lavender oil as a potential option for mild to moderate anxiety. While not a replacement for conventional therapy in severe cases, lavender is supported by both traditional use and moderate-to-strong scientific evidence for anxiety relief, justifying its role as an adjunct or alternative in certain situations.

More about lavender
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Other ingredients used for Anxiety Disorders

5-Hydroxytryptophan (5-HTP)
7,8-Dihydroxyflavone
Aconite
Albizia
amino acids
apigenin
ashwagandha
Bacopa
Bacopin
bacoside
Baikal Skullcap
beta caryophyllene
Bifidobacterium adolescentis
Bifidobacterium infantis
Bifidobacterium longum
brahmi
cannabidiol
Cannabis sativa oil
Capitate Valerian
catnip
Centella asiatica
chamomile
Clary sage
cocoa
Convolvulus pluricaulis
Convolvulus prostratus
cowslip
curcumin
Cymbopogon martini
essential oil blend
gastrodin
Gelsemium
ginkgo biloba
Ginkgoside
ginseng
gotu kola
green tea
Griffonia simplicifolia
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
Honokiol
hyperforin
Hypericum
inositol
jujubosides
kava
kavalactones
Kefir
L-glycine
L-taurine
L-theanine
L-tryptophan
lactium casein decapeptide
Lactobacillus
Lactobacillus casei
Lactobacillus paracasei
Lactobacillus rhamnosus
Lactococcus rhamnosus
Large-leaved linden
Lavandin
lavender
lemon balm
linalool
linden
lion's mane
lithium orotate
magnesium
magnolia
magnolol
Matcha
Melatonin
Mesembrine
Mimulus
Monoterpenes
Motherwort
Muira puama
Mulungu
N-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
Passionfruit
phosphatidylserine
phytocannabinoids
Polygala
polygala root
prebiotic blend (proprietary)
pregnenolone
probiotics
Pulsatilla
Purple Monkeyflower
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
Rhodiola
rosavins
rosmarinic acid
Safranal
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
Sandalwood
sceletium
Scleranthus annus
Shankhpushpi
shen-chu
skullcap
Spikenard
St. John's Wort
star of Bethlehem
Tea
Terpenoids
Tetrahydropalmatine
Trichilia catigua
Valerenic acid
Valerian root
velvet bean
Vervain
vitamin B
vitamin B12
vitamin B6
Vitexin
Waterhyssop
Wogonin
Yohimbine
Zinc