Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Leptospermum scoparium, commonly known as manuka, is primarily known for the antimicrobial properties of its honey (manuka honey), which have been validated in numerous scientific studies. The essential oils and extracts from the plant also exhibit antibacterial and antifungal activity in vitro. Manuka honey, in particular, contains unique compounds such as methylglyoxal (MGO) and dihydroxyacetone, which contribute to its broad-spectrum antimicrobial effects, including activity against antibiotic-resistant bacteria like Staphylococcus aureus (MRSA). Clinical studies have demonstrated that manuka honey can be effective in wound care—promoting healing and reducing infection rates—sometimes when conventional antibiotics fail or are contraindicated. The evidence is strongest for topical use (wounds, ulcers) rather than systemic infections. While traditional Māori and Australian Aboriginal medicine utilized Leptospermum scoparium for its healing properties, modern validation centers on manuka honey rather than other plant parts. The use of manuka honey as an alternative or adjunct to antibiotics is supported by moderate scientific evidence, but it is not a direct replacement for systemic antibiotic therapy. Most experts recommend its use mainly in wound management rather than for treating internal bacterial infections.

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