Evidence supporting the use of: Fructo-Oligosaccharides
For the health condition: Antibiotics (alternatives to)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Fructo-oligosaccharides (FOS) are short-chain carbohydrates classified as prebiotics, meaning they selectively stimulate the growth and activity of beneficial gut bacteria such as Bifidobacteria and Lactobacilli. Their use as an alternative or adjunct to antibiotics is based on the premise that a healthy, balanced microbiota can suppress the growth of pathogenic organisms and help maintain intestinal health, especially after or during antibiotic therapy.
There is emerging scientific evidence supporting the role of FOS in promoting gut health and potentially reducing the risk of infections by inhibiting pathogen adhesion and enhancing the gut barrier. However, FOS itself does not possess direct antibacterial activity and is not considered a replacement for antibiotics in treating active bacterial infections.
Some clinical studies have shown that FOS supplementation can help restore gut microbiota after antibiotic treatment and may reduce the duration or severity of certain infections, particularly in the gastrointestinal tract. However, the evidence is still limited, with most studies being small, of short duration, or focused on prevention rather than treatment. Systematic reviews and meta-analyses conclude that while FOS can support gut health and reduce antibiotic-associated side effects like diarrhea, there is insufficient evidence to recommend FOS as an alternative to antibiotics for treating infections.
In summary, FOS is scientifically validated as a supportive agent for gut microbiota, especially during or after antibiotic use, but not as a direct alternative to antibiotics for infection treatment. The evidence level is moderate but not robust (rated 2/5).
More about Fructo-Oligosaccharides
More about Antibiotics (alternatives to)
Other ingredients used for Antibiotics (alternatives to)
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bacillus clausii
bacillus subtilis
berberine
black cumin
black walnut
caprylic acid
caterpillar mushroom
clove
colostrum
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turmeric
curcumin
epigallocatechin gallate (EGCG)
garlic bulb
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goldenseal
gooseberry
green tea
horseradish
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honeysuckle
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Lactobacillus paracasei
lactiplantibacillus plantarum
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lauric acid
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Monolaurin
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oregon grape
oyster mushroom
phenolic compounds
plantain
butyric acid
rhizome
sage
shiitake mushroom
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vitamin C
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papaya
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pistacia integerrima gall
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alpha-terpineol
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bee propolis
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betulinic acid
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bee products
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benzyl isothiocyanate
baicalin
coconut
capric acid
Calotropis gigantea
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cinnamic acid
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cinnamaldehyde
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Dichrostachys glomerata
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flavonoids
Fomes fomentarius
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gallic acid
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honey
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isoquinoline alkaloids
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Litsea
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lysozyme
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Onosma bracteatum
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polysaccharides
pagoda tree
polylysine
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phlorotannins
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Solanum indicum
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saponins
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Other health conditions supported by Fructo-Oligosaccharides
Antibiotics (alternatives to)Cancer Treatment (reducing side effects)
Cholesterol (high)
Colitis
Constipation (adults)
Constipation (children)
Crohn's Disease
Diabetes
Diarrhea
Digestion (poor)
Fatty Liver Disease
Indigestion
Inflammation
Inflammatory Bowel Disorders