Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Chalcone is a naturally occurring compound found in many plants and is a precursor for various biologically active flavonoids. There is emerging scientific interest in chalcone and its derivatives due to their antimicrobial properties. Several in vitro studies have demonstrated that chalcone compounds exhibit antibacterial activity against both Gram-positive and Gram-negative bacteria, including drug-resistant strains. Proposed mechanisms include disruption of bacterial cell walls, inhibition of efflux pumps, and interference with nucleic acid synthesis. However, most of the evidence comes from cell culture studies or, less frequently, animal models; there are currently no robust human clinical trials validating chalcone as a direct alternative to conventional antibiotics.

Chalcone is not traditionally used as an "antibiotic alternative" in herbal or folk medicine, but its antimicrobial potential has attracted attention in medicinal chemistry as a lead compound for novel antibiotic development. The rating is 2 because, while there is promising preclinical evidence and a plausible mechanism of action, there is insufficient clinical evidence to support its use as a replacement for standard antibiotics in humans. Further research, particularly clinical trials, is needed before chalcone or its derivatives can be recommended for this purpose.

More about Chalcone
More about Antibiotics (alternatives to)

Other ingredients used for Antibiotics (alternatives to)

2'-Fucosyllactose
ajoene
astragalus
bacillus clausii
bacillus subtilis
berberine
black cumin
black walnut
caprylic acid
caterpillar mushroom
clove
colostrum
Coptis chinensis
turmeric
curcumin
epigallocatechin gallate (EGCG)
garlic bulb
ginger
goldenseal
gooseberry
green tea
horseradish
Indian tinospora
honeysuckle
lactobacillus bulgaricus
lactobacillus fermentum
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
lactoperoxidase
lauric acid
lentinula edodes mycelia
LH01-myoviridae
mastic gum
monolaurin
oregano
oregon grape
oyster mushroom
phenolic acids
plantain
butyric acid
rhizome
sage
shiitake mushroom
thyme
vitamin C
wasabia japonica
zinc
yellow root
papaya
neem tree
clerodendrum indicum
pistacia integerrima gall
paederia foetida
pau d'arco
myrrh
morinda
oriental arborvitae
melaleuca alternifolia
algae
geranium
10-Hydroxy-2-Decanoic Acid
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
3-Phenyllactic Acid
Alpha-terpineol
Azelaic acid
Allicin
Anamu
Alchornea
Aucubin
Andrographolide
Andrographis
Alsonia scholaris
Asteracea
Allyl Sulfide
Acemannan
Algal protein
Alliin
Alantolactone
Bee Propolis
Bacillus indicus
Baphicacanthus cusia
Bidens pilosa
Betulinic acid
Butea monosperma
Brazillian peppertree
Bee hive
Basidiomycota
Bacillus licheniformis
Brevibacillus laterosporus
Bee products
Bombax
Borassus aethiopum
Bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
Baicalin
Coconut
Capric Acid
Calotropis gigantea
coconut oil
Carvacrol
Chinese Raisintree
Cinnamic Acid
Citral
Centipeda
Chalcone
Clostridium butyricum
Cinnamaldehyde
Copaiba Oil
Dichrostachys glomerata
European Elder
Embelia
Eugenol
Flavonoids
Fomes fomentarius
Gallic Acid
Glyceryl monolaurate
Garlic
Golden Shower Tree

Other health conditions supported by Chalcone

Antibiotics (alternatives to)
Cancer (natural therapy for)
Cancer (prevention)
Diabetes
Fungal Infections
Inflammation

Products containing Chalcone

We currently have no products on Caring Sunshine that contain this ingredient.