Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin C (ascorbic acid) is scientifically validated as a supportive agent in the management of certain types of anemia, particularly iron deficiency anemia. The primary mechanism is its ability to enhance the absorption of non-heme iron (the form of iron found in plant-based foods) in the gastrointestinal tract. Vitamin C reduces ferric iron (Fe3+) to ferrous iron (Fe2+), the latter of which is more readily absorbed by intestinal mucosal cells. Numerous clinical studies have demonstrated that consuming vitamin C with iron-rich foods or supplements can significantly increase serum ferritin and hemoglobin levels in individuals with iron deficiency anemia.

Guidelines from organizations such as the World Health Organization and the Centers for Disease Control and Prevention recommend co-administration of vitamin C with oral iron therapy to maximize iron absorption. A 2019 randomized controlled trial published in The Lancet Haematology confirmed that vitamin C supplementation improved the efficacy of oral iron in anemic patients, though some recent studies suggest that very high doses may not offer additional benefit over dietary amounts.

Historically, vitamin C has not been used as a primary treatment for anemia, but its role as an iron absorption enhancer is well established in modern clinical practice. It is not effective for anemia unrelated to iron deficiency (such as anemia of chronic disease or hemolytic anemia). In summary, vitamin C is scientifically justified as adjunctive therapy for iron deficiency anemia, with moderate to strong evidence supporting its use.

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Other ingredients used for Anemia

Other health conditions supported by vitamin C

Products containing vitamin C

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