Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Fish oil, rich in omega-3 fatty acids like EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), has been studied for its potential benefits in Alzheimer's Disease (AD) due to its role in brain health and anti-inflammatory effects. Observational studies have shown that populations with higher fish consumption tend to have lower rates of cognitive decline. DHA, a major structural component of brain tissue, is thought to protect against neurodegeneration, reduce inflammation, and support synaptic plasticity.

However, clinical trial results are mixed. Some randomized controlled trials suggest that omega-3 supplementation may benefit individuals with mild cognitive impairment or very early Alzheimer's, showing modest improvements in memory and cognitive function. For example, a 2010 study published in Alzheimer's & Dementia found slight cognitive benefits in patients with mild AD, but not in those with moderate to severe disease. Other large trials, such as the OmegAD study, did not find significant benefit in established AD.

Current scientific consensus is that fish oil supplementation is not effective as a treatment for established Alzheimer's Disease, but may have some preventative or very early-stage benefit. As such, guidelines do not recommend fish oil as a primary therapy for AD, though it is considered low-risk. More research is needed, especially in targeted populations and at different disease stages.

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Products containing fish oil

Nature's Sunshine Circulatory System
Nature's Sunshine DHA
Nature's Sunshine Krill Oil (With Vitamin K2)
Nature's Sunshine Super Omega 3 EPA
Nature's Sunshine Super Omega 3 EPA
Nature's Sunshine Super Trio