Evidence supporting the use of: Selenium
For the health condition: Aging (prevention)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Selenium is a trace mineral with antioxidant properties, and its role in aging and age-related diseases has been the subject of scientific investigation. Selenium is a cofactor for the enzyme glutathione peroxidase, which helps protect cells from oxidative damage by neutralizing free radicals. Since oxidative stress is a known contributor to the aging process and the development of age-related conditions, selenium has been hypothesized to have anti-aging benefits. Some population studies have observed that individuals with higher selenium status tend to have better cognitive function and may experience lower rates of age-related diseases, such as cardiovascular disease and certain cancers.

However, the evidence supporting selenium supplementation specifically for the prevention of aging in healthy adults is limited and mixed. Large randomized controlled trials, such as the SELECT trial, have not shown clear benefits of selenium supplementation in reducing the risk of major age-related diseases in well-nourished populations. There is also evidence that both selenium deficiency and excess can be harmful, and the margin between optimal and excessive intake is narrow. While selenium is essential for health and its deficiency can accelerate aging-related decline, supplementation beyond dietary needs does not have robust evidence for preventing aging itself. Thus, while there is a scientific rationale and some supporting data, the overall quality of evidence is low to moderate.

More about selenium
More about Aging (prevention)

Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine
Flavonoids
Fo-Ti
Fucoxanthin
fibroblast growth factor
Ginsenosides
Gac
Gerovital H3
Glabridin