Evidence supporting the use of: Magnesium
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Magnesium is an essential mineral involved in hundreds of enzymatic reactions in the human body, including those related to energy production, DNA repair, and cellular aging processes. Scientific interest in magnesium’s role in aging stems from its impact on oxidative stress, inflammation, and mitochondrial function—factors closely linked to age-related decline. Several observational studies have found associations between higher magnesium intake and reduced risk of chronic diseases common with aging, such as cardiovascular disease, type 2 diabetes, and osteoporosis. Magnesium deficiency has also been linked to increased markers of inflammation and accelerated cellular aging, such as telomere shortening.

Some interventional studies suggest that magnesium supplementation may improve muscle function, cognitive performance, and bone health in older adults. For example, randomized controlled trials have demonstrated improvements in muscle strength and physical performance in elderly individuals with low magnesium status who were supplemented with magnesium. However, it is important to note that direct evidence showing magnesium supplementation slowing or reversing the biological aging process in humans is limited. Most clinical trials focus on specific age-related conditions rather than overall aging.

In summary, while magnesium’s role in supporting healthy aging is scientifically plausible and supported by moderate evidence for certain age-related conditions, more robust, long-term clinical trials are needed to fully validate its efficacy as an anti-aging intervention. Its use in aging prevention is based on both mechanistic rationale and some supportive human data.

More about magnesium
More about Aging (prevention)

Other ingredients used for Aging (prevention)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
7-hydroxymatairesinol (HMR)
7-Keto-DHEA
8-Prenylnaringenin
Abalone
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
Algae
algal oil
Algal protein
Allantoin
Almond fruit
Alpha hydroxy acids
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anemarrhena asphodeloides
anserine
anthocyanidins
anthocyanins
anthocyanosides
antler
Antrodia camphorata
apigenin
apple
apricot
argan nut oil
Aronia melanocarpa
ascorbyl palmitate
ashitaba
ashwagandha
astaxanthin
astragaloside
astragalus
avocado
beta-carotene
bioflavonoids
bird\'s nest
Brassica
Brussel sprouts
Carnosine
carotene (unspecified)
carrot
catalase
cauliflower
Chinese Ligustrum berry
cistanche
coenzyme Q10 (CoQ10)
collagen
cruciferous
cryptoxanthin
curcumin
Curcuminoid
cycloastragenol
DHEA
DHEA (dehydroepiandrosterone)
dismutase
dodder
Dunaliella
Dunaliella salina
ellagic acid
epicatechin
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
ergothioneine
fibroblast growth factor
fisetin
flavonoids
flaxseed
fo-ti
fucoxanthin
Gac
Gerovital H3
ginkgo biloba
Ginsenosides
Glabridin
goji berry
green tea
greens blend (proprietary)
Haematococcus pluvialis
hazelnut
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
L-carnosine
lutein
Lycium
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oolong tea
Peptides
Phytoene
Phytofluene
polypeptide complex (proprietary)
polyphenols
protein
pyrroloquinoline quinone
quercetin
resveratrol
Rhodiola
royal jelly
Salidroside
selenium
Shilajit
silicon
soy isoflavones
soybean
Squalene
Trans-pterostilbene
Tremella
Triterpenes
turmeric
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
Watermelon
Xanthophyll
Yerba mate
Zinc
β-nicotinamide mononucleotide (NMN)

Other health conditions supported by magnesium

Addictions (drugs)
Addictions (general remedies for)
Aging (prevention)
Alcoholism
Alkalosis
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Control (countering side effects)
Body Building
Body Odor
Boils
Broken Bones
Bronchitis
Bulimia
Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Colon (atonic)
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Exercise
Fatigue
Fibromyalgia Syndrome
Headache (cluster)
Headache (tension)
Hearing Loss
Heart (weakness)
Mental Illness
Migraine
Mood Swings
Muscle Tone (lack of)
Nerve Damage
Nervous Exhaustion
Nervousness
Neurosis
Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
Senility
Shock
Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
Sugar Cravings
Surgery (healing from)
Surgery (preparation for)
Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores
Adrenal Fatigue
Abscesses
Allergies (respiratory)
Abdominal Pain
Acid Indigestion
Cholesterol (high)
Circulation (poor)
Constipation (adults)
Convulsions
Cramps (leg)
Cramps (menstrual)
Cramps and Spasms
Depression
Diabetes
Digestion (poor)
Dizziness
Gastritis
Headache (general)
Heart Fibrillation or Palpitations
Hypertension
Insomnia