Evidence supporting the use of: Magnesium
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Magnesium is an essential mineral involved in hundreds of enzymatic reactions in the human body, including those related to energy production, DNA repair, and cellular aging processes. Scientific interest in magnesium’s role in aging stems from its impact on oxidative stress, inflammation, and mitochondrial function—factors closely linked to age-related decline. Several observational studies have found associations between higher magnesium intake and reduced risk of chronic diseases common with aging, such as cardiovascular disease, type 2 diabetes, and osteoporosis. Magnesium deficiency has also been linked to increased markers of inflammation and accelerated cellular aging, such as telomere shortening.

Some interventional studies suggest that magnesium supplementation may improve muscle function, cognitive performance, and bone health in older adults. For example, randomized controlled trials have demonstrated improvements in muscle strength and physical performance in elderly individuals with low magnesium status who were supplemented with magnesium. However, it is important to note that direct evidence showing magnesium supplementation slowing or reversing the biological aging process in humans is limited. Most clinical trials focus on specific age-related conditions rather than overall aging.

In summary, while magnesium’s role in supporting healthy aging is scientifically plausible and supported by moderate evidence for certain age-related conditions, more robust, long-term clinical trials are needed to fully validate its efficacy as an anti-aging intervention. Its use in aging prevention is based on both mechanistic rationale and some supportive human data.

More about magnesium
More about Aging (prevention)

Other ingredients used for Aging (prevention)

7-hydroxymatairesinol (HMR)
7-Keto-DHEA
acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
amino acids
anthocyanins
apple
apricot
ascorbyl palmitate
ashwagandha
astaxanthin
astragalus
beta-carotene
brussel sprouts
carrot
catalase
cauliflower
coenzyme Q10 (CoQ10)
collagen
cryptoxanthin
turmeric
curcumin
DHEA (dehydroepiandrosterone)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
ginkgo biloba
green tea
greens blend (proprietary)
l-carnosine
lutein
magnesium
matcha
melatonin
mixed carotenoids
nicotinamide riboside
omega-3 fatty acids
polypeptide complex (proprietary)
protein
quercetin
resveratrol
rhodiola
sardines
selenium
silicon
soybean
trans-pterostilbene
almond fruit
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
watermelon
zinc
β-nicotinamide mononucleotide (NMN)
cistanche
dodder
royal jelly
polyphenols
anemarrhena asphodeloides
yerba mate
goji berry
algae
AMP-activated protein kinase (AMPK)
soy isoflavones
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
8-Prenylnaringenin
Antler
Apigenin
Aronia melanocarpa
Antrodia camphorata
Anserine
Avocado
Alpha Hydroxy Acids
Allantoin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Algal protein
anthocyanosides
Argan nut oil
Abalone
Brassica
Bioflavonoids
Bird's nest
Carnosine
Curcuminoid
Cruciferous
Cycloastragenol
Chinese Ligustrum berry
Carotene (unspecified)
Dunaliella salina
Dismutase
DHEA
Dunaliella
Epidermal Growth Factor
epicatechin
Ellagic Acid
Ergothioneine

Other health conditions supported by magnesium

Abdominal Pain
Abscesses
Acid Indigestion
Addictions (drugs)
Addictions (general remedies for)
Adrenal Fatigue
Aging (prevention)
Alcoholism
Alkalosis
Allergies (respiratory)
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Control (countering side effects)
Body Building
Body Odor
Boils
Broken Bones
Bronchitis
Bulimia
Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Cholesterol (high)
Circulation (poor)
Colon (atonic)
Constipation (adults)
Convulsions
Cramps (leg)
Cramps (menstrual)
Cramps and Spasms
Depression
Diabetes
Digestion (poor)
Dizziness
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Exercise
Fatigue
Fibromyalgia Syndrome
Gastritis
Headache (cluster)
Headache (general)
Headache (tension)
Hearing Loss
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Insomnia
Mental Illness
Migraine
Mood Swings
Muscle Tone (lack of)
Nerve Damage
Nervous Exhaustion
Nervousness
Neurosis
Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
Senility
Shock
Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
Sugar Cravings
Surgery (healing from)
Surgery (preparation for)
Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores

Products containing magnesium

Nature's Sunshine CleanStart Mild
Nature's Sunshine Adrenal Support
Nature's Sunshine AIVIA Hydrate
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AnxiousLess
Nature's Sunshine AnxiousLess
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Calcium Plus Vitamin D
Nature's Sunshine Cellular Energy
Nature's Sunshine Chromium-GTF
Nature's Sunshine Coral Calcium
Nature's Sunshine Coral Calcium
Nature's Sunshine Fibralgia
Nature's Sunshine Free Amino Acids
Nature's Sunshine Gentle Move
Nature's Sunshine Glandular System
Nature's Sunshine Heavy Metal Detox
Nature's Sunshine Magnesium
Nature's Sunshine Magnesium Complex
Nature's Sunshine Mega-Chel
Nature's Sunshine Mind-Max
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Power Beets Pouch
Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Sea Calcium (Nature's)
Nature's Sunshine Sunshine Heroes Whole Food Papayazyme
Nature's Sunshine Silver Shield BioGuard Hand & Body Cream
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Urinary Maintenance
Nature's Sunshine Urinary System
Nature's Sunshine VitaWave