Evidence supporting the use of: Flaxseed
For the health condition: Aging (prevention)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flaxseed is often promoted for its potential anti-aging benefits, largely due to its rich content of alpha-linolenic acid (ALA, an omega-3 fatty acid), lignans (phytoestrogens), and antioxidants. Scientific studies have investigated these compounds in relation to aging processes, such as oxidative stress, inflammation, and skin aging. The omega-3 fatty acids in flaxseed may help reduce systemic inflammation, a key contributor to age-related diseases like cardiovascular disease and cognitive decline. Lignans in flaxseed also exhibit antioxidant properties that may protect cells from oxidative damage associated with aging.

Some small clinical trials and animal studies suggest that flaxseed supplementation can improve skin hydration and elasticity, reduce skin roughness, and lower markers of inflammation and oxidative stress. However, the evidence is limited in scope and quality, with most studies being short-term or using surrogate endpoints rather than direct measures of aging or longevity. There is a lack of large, long-term, randomized controlled trials specifically examining flaxseed’s effect on aging prevention or lifespan extension in humans.

Overall, while there is some scientific rationale and preliminary evidence supporting the use of flaxseed for aspects of healthy aging, the current evidence is moderate at best (rating: 2/5). More rigorous clinical research is required before flaxseed can be confidently recommended for aging prevention.

More about flaxseed
More about Aging (prevention)

Other ingredients used for Aging (prevention)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
7-hydroxymatairesinol (HMR)
7-Keto-DHEA
8-Prenylnaringenin
Abalone
Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
Algae
algal oil
Algal protein
Allantoin
Almond fruit
Alpha hydroxy acids
Alpha-carotene
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-linolenic acid (ALA)
alpha-lipoic acid
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
anemarrhena asphodeloides
anserine
anthocyanidins
anthocyanins
anthocyanosides
antler
Antrodia camphorata
apigenin
apple
apricot
argan nut oil
Aronia melanocarpa
ascorbyl palmitate
ashitaba
ashwagandha
astaxanthin
astragaloside
astragalus
avocado
beta-carotene
bioflavonoids
bird\'s nest
Brassica
Brussel sprouts
Carnosine
carotene (unspecified)
carrot
catalase
cauliflower
Chinese Ligustrum berry
cistanche
coenzyme Q10 (CoQ10)
collagen
cruciferous
cryptoxanthin
curcumin
Curcuminoid
cycloastragenol
DHEA
DHEA (dehydroepiandrosterone)
dismutase
dodder
Dunaliella
Dunaliella salina
ellagic acid
epicatechin
Epidermal Growth Factor
epigallocatechin gallate (EGCG)
ergothioneine
fibroblast growth factor
fisetin
flavonoids
flaxseed
fo-ti
fucoxanthin
Gac
Gerovital H3
ginkgo biloba
Ginsenosides
Glabridin
goji berry
green tea
greens blend (proprietary)
Haematococcus pluvialis
hazelnut
HMB hydroxymethylbutyrate
hydroxymethylbutyrate
icariin
L-carnosine
lutein
Lycium
magnesium
Matcha
Melatonin
mixed carotenoids
nicotinamide riboside
Oligomeric proanthocyanidins
omega-3 fatty acids
oolong tea
Peptides
Phytoene
Phytofluene
polypeptide complex (proprietary)
polyphenols
protein
pyrroloquinoline quinone
quercetin
resveratrol
Rhodiola
royal jelly
Salidroside
selenium
Shilajit
silicon
soy isoflavones
soybean
Squalene
Trans-pterostilbene
Tremella
Triterpenes
turmeric
Urolithin A
vegetable blend (proprietary)
vitamin A
vitamin C
vitamin E
Watermelon
Xanthophyll
Yerba mate
Zinc
β-nicotinamide mononucleotide (NMN)