Evidence supporting the use of: Trace minerals
For the body system: Adrenal Glands

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Trace minerals, such as zinc, magnesium, selenium, and copper, play essential roles in numerous physiological processes, including those related to the adrenal glands. The adrenal glands produce hormones like cortisol and aldosterone, which are critical for stress response, metabolism, and electrolyte balance. Scientific studies have shown that deficiencies in certain trace minerals can negatively impact adrenal function. For example, zinc is required for proper hormone production, and magnesium is involved in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Selenium acts as an antioxidant, protecting adrenal tissues from oxidative stress. However, while animal and in vitro studies suggest trace minerals are important for adrenal health, robust human clinical trials specifically showing that trace mineral supplementation improves adrenal function in healthy individuals are limited. Most evidence comes from studies on deficiency states rather than supplementation in the general population. Overall, while there is a scientific basis for the importance of trace minerals in adrenal health, direct evidence supporting the use of supplemental trace minerals to "support" or "boost" adrenal gland function, especially in the absence of deficiency, remains modest.

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