Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Prebiotic blends, which typically contain fibers such as inulin, fructooligosaccharides (FOS), or galactooligosaccharides (GOS), are used in some products aimed at supporting digestive health, including acid indigestion. The scientific justification for their use in acid indigestion is modest. Prebiotics can alter the gut microbiota, increasing populations of beneficial bacteria like Bifidobacterium and Lactobacillus. There is emerging evidence that imbalances in gut microbiota may play a role in gastrointestinal symptoms, including dyspepsia and acid indigestion. Some studies have shown that prebiotics may help improve overall gut function, reduce inflammation, and support mucosal barrier integrity, which could, in theory, alleviate symptoms of indigestion. However, clinical trials specifically evaluating prebiotic blends for the treatment or prevention of acid indigestion (heartburn, dyspepsia, or reflux) are limited and results are mixed. Most evidence is indirect, focusing on general digestive health rather than targeted relief of acid-related symptoms. Therefore, while there is a plausible mechanism and some supportive data, the direct evidence for prebiotic blends as a treatment for acid indigestion is currently weak, justifying a modest rating.

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