Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Maytenus ilicifolia, commonly known as "espinheira-santa," has a long history of traditional use in South America, particularly in Brazil, for the treatment of acid indigestion, gastritis, and peptic ulcers. The traditional use is primarily based on ethnobotanical knowledge passed down through generations, as indigenous and rural populations employed the leaves as an herbal remedy for gastrointestinal complaints. The plant is thought to exert a protective effect on the gastric mucosa and to reduce gastric acidity, which may alleviate symptoms of acid indigestion.

Regarding scientific evidence, a limited number of preclinical studies (mainly in vitro and animal models) have suggested that extracts of Maytenus ilicifolia possess cytoprotective and anti-ulcerogenic properties, possibly due to the presence of flavonoids, tannins, and triterpenes. However, robust clinical trials in humans are lacking, and the available evidence does not reach the standard required for strong scientific validation. The plant is included in some official herbal pharmacopeias in South America for digestive complaints, which reflects its established traditional use rather than solid scientific endorsement.

In summary, the use of Maytenus ilicifolia to support or treat acid indigestion is justified by traditional evidence, with only modest support from preliminary scientific studies. More rigorous clinical research is needed to fully substantiate its efficacy and safety for this indication.

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