Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Physalis angulata, commonly known as cutleaf groundcherry, has been traditionally used in various cultures for the treatment of abscesses and other skin infections. Ethnobotanical surveys in regions such as Indonesia, India, and parts of South America report its application as a poultice or topical preparation to address localized skin infections, including abscesses, boils, and sores. The traditional rationale is often based on observed anti-inflammatory and antimicrobial effects, as well as the plant's general use in folk medicine for "drawing out" infections or reducing swelling.

From a scientific standpoint, preliminary studies have demonstrated that extracts of Physalis angulata possess antimicrobial and anti-inflammatory properties in vitro and in animal models. For example, certain steroidal lactones (physalins) and flavonoids isolated from the plant have shown activity against some bacteria and fungi. However, direct clinical studies or robust experimental evidence specifically validating its efficacy for the treatment of abscesses in humans are lacking. Thus, while the traditional use is well-documented and there is some scientific rationale based on the plant's bioactive compounds, the evidence is not strong or specific enough to warrant a high rating. The use of Physalis angulata for abscesses remains primarily supported by tradition, with low-to-moderate scientific backing.

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