Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Aescin (also known as escin) is a mixture of saponins extracted from the seeds of the horse chestnut tree (Aesculus hippocastanum). Its use in supporting or treating varicose veins is supported by scientific evidence. Clinical studies and meta-analyses have shown that aescin has beneficial effects on chronic venous insufficiency (CVI), a condition closely related to varicose veins. The mechanism of action appears to involve reducing capillary permeability, improving venous tone, and exerting anti-inflammatory effects, which together help decrease edema, pain, and other symptoms associated with venous disorders.

Randomized controlled trials and systematic reviews (e.g., Cochrane Reviews) have found that standardized horse chestnut seed extracts containing aescin can significantly reduce leg pain, swelling, and itching compared to placebo in patients with CVI. The evidence suggests aescin is as effective as compression therapy in mild to moderate cases, although it is not a substitute for more advanced medical interventions when necessary. Aescin is generally well tolerated, with adverse effects being mild and infrequent (e.g., gastrointestinal discomfort, dizziness).

In summary, the use of aescin for varicose veins and related venous insufficiency is supported by moderate to strong scientific evidence, with multiple clinical trials and systematic reviews backing its efficacy and safety for symptom relief.

More about Aescin
More about Varicose Veins

Other ingredients used for Varicose Veins

Other health conditions supported by Aescin

Products containing Aescin