Evidence supporting the use of: Selenium
For the body system: Testes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenium is a trace mineral that plays a crucial role in male reproductive health, particularly in the testes. Scientific studies have shown that selenium is a vital component of selenoproteins, including glutathione peroxidase, which protect cells from oxidative damage. The testes are highly susceptible to oxidative stress due to the high rate of cell division during spermatogenesis. Research indicates that selenium supplementation can improve sperm quality, motility, and overall fertility in men with low selenium status. Several human and animal studies have found that selenium deficiency is associated with impaired spermatogenesis, reduced testosterone production, and even infertility. For example, a 2011 review in the journal Biological Trace Element Research concluded that selenium supplementation in subfertile men may improve sperm motility and morphology. However, the evidence is mixed, and excessive selenium intake can be harmful. Most benefits are observed in individuals with selenium deficiency rather than the general population. In summary, the use of selenium to support the testes and male reproductive function has scientific backing, especially related to its antioxidant properties and its role in sperm production and testosterone synthesis, but more high-quality, large-scale studies are needed to establish definitive recommendations.

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