Evidence supporting the use of: Folate
For the body system: Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Folate, also known as vitamin B9, is scientifically validated as an essential nutrient for supporting the reproductive system, particularly in women of childbearing age. Robust evidence demonstrates that adequate folate intake before and during early pregnancy is crucial for proper fetal neural tube development and significantly reduces the risk of neural tube defects (NTDs) such as spina bifida and anencephaly. These findings have led to widespread public health recommendations for folic acid supplementation among women who are planning to conceive or are pregnant. In addition to its role in neural development, folate is involved in DNA synthesis, repair, and methylation, processes vital for cell division and embryonic growth. Deficiency in folate can also lead to reproductive complications, including infertility and pregnancy loss. The Centers for Disease Control and Prevention (CDC), World Health Organization (WHO), and numerous peer-reviewed clinical trials and epidemiological studies have established the importance of folate in reproductive health. Consequently, folate fortification in foods has been implemented in many countries and has demonstrably decreased the incidence of NTDs. The scientific support for folate’s role in the reproductive system is among the strongest for any nutrient, justifying its use and recommendation for reproductive health support.

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Other ingredients that support Reproductive System

Acetyl L-carnitine
amino acids
ashwagandha
beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
Chinese salvia root
choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaenoic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-arginine
l-carnitine
Lactobacillus crispatus
Lactobacillus jensenii
licorice root
lignans
linoleic acid (LA)
maca
magnesium
Marine lipid
Melatonin
Moringa
Motherwort
Muira puama
omega-3 fatty acids
omega-6 fatty acids
pomegranate
protein
pumpkin
quail egg
raspberry
rehmannia glutinosa
saffron
saw palmetto
selenium
selenium
soybean
spearmint leaf
Tongkat ali
tribulus
vitamin A
vitamin B
vitamin D
vitamin E
vitamin E
seaweed
Water
Wild yam
Zinc
sarsaparilla
red clover
suma
squawvine
Mugwort
nut grass
anise
punarnava
smilax
chaff flower
Szechuan lovage
Yarrow
cistanche
dioscorea
dodder
eucommia
ganoderma
lotus seed
Morinda
royal jelly
equol (proprietary)
guelder rose
trace minerals
anemarrhena asphodeloides
purslane
barrenwort
shepherd's purse
Wood betony
herbal blend (proprietary)
Yohimbe
25-d-spirosta-3, 5-diene
5-methyltetrahydrofolate glucosamine
8-Prenylnaringenin
antler
arachidonic acid
Achyranthes
anamu
Alchemilla
Aletris
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Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Abuta
Allium tuberosum
animal protein
blue cohosh
babchi
Baliospermum
black galingale
beef
Beef liver
bugbane
Bulbine natalensis
black gram
banyan
ba ji tian
barbasco
bee products
Borassus aethiopum
banana
Boerhavia diffusa
Calochortus
Curculigo orchioides
cohosh
Clary sage
Chinese mountain ant
Cucurbita
cod liver oil
Codonopsis
Cnidium
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Chlorophytum
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casticin
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catuaba
costus
Carthamus
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DHEA
daidzein
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dong quai
dibenzo-alpha pyrones
D-Pinitol
diosgenin
date
eurycomanone
egg
Euryale seed
elk antler
Eurycoma Longifolia
eicosapentaenoic acid
Embelia
estrogen
folic acid
Flueggea suffruticosa
fo-ti
furostanols
formononetin
fish
fatty acids
false unicorn root
Fadogia agrestis
Ginsenosides
Guava
giant trillium
horny goat weed
Herb Robert
Indian sarsparilla
isoflavones
long pepper
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Indian fagonia
inositol phosphate
jungli-bean
Jatropha macrantha
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ligustilides
lodhtree
lotus
Leptadenia
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lipids
Labisia pumila
macamides
maral root
Mezoneuron benthamianum
Montanoa tomentosa
Matico
Matapalo Tree
Miroestrol
Marine fat
mandrake
Millettia
macaenes
Nigella seed
Ocotillo
Orchis latifolia
orchid
Osthole
Puerain
Phyllanthus
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Piper chaba
Propionyl-L-Carnitine
polyunsaturated fat
Protodioscin
probiotics
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Paris polyphylla
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Peptides
rue
Rubus
Rehmannia
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Rosa laevigata
Sapogenin
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Soy
Selenomethionine
Salvia
Sensitive Plant
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Shataverins
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Sparganium
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Trichilia catigua
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Tribulus Terrestris
Vegetable Protein
Vitexicarpin
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Vitex Agnus-Castus
Withanolides
Yohimbine
Zedoary