Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Guazuma ulmifolia, commonly known as "Guacimo," has a history of traditional use in various regions of Central and South America for treating parasitic infections, particularly intestinal worms (helminths). Ethnobotanical reports document its use among indigenous and rural communities, where decoctions or infusions of the bark, leaves, or fruits are administered as a folk remedy for intestinal parasites. The rationale for its use in traditional medicine is largely based on empirical observations and longstanding practices rather than on rigorous scientific validation.

Scientific studies on the anthelmintic (anti-worm) activity of Guazuma ulmifolia are limited. Some in vitro and animal model studies suggest mild to moderate activity against certain nematodes, but the results are generally not robust or consistent. For example, a few laboratory experiments have noted some inhibitory effects on the motility or survival of nematodes, but these findings are preliminary and have not translated into clinical recommendations. Most scientific reviews conclude that there is insufficient evidence to confirm efficacy against parasites in humans.

In summary, the use of Guazuma ulmifolia for treating parasitic infections is primarily justified by traditional knowledge, with only low-level preliminary scientific evidence supporting this claim. More rigorous research is needed to substantiate its potential anthelmintic properties.

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