Evidence supporting the use of: Vitamin D
For the body system: Lungs

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin D plays a well-documented role in immune function, and there is a growing body of scientific research exploring its impact on lung health. Several observational studies have found that individuals with low vitamin D levels are at increased risk for respiratory infections, such as influenza and pneumonia. Randomized controlled trials have shown that vitamin D supplementation can modestly reduce the risk of acute respiratory tract infections, particularly in individuals who are deficient in vitamin D (BMJ 2017 meta-analysis). Furthermore, there is evidence suggesting that vitamin D may play a role in reducing the severity and frequency of asthma attacks, especially in children and adults with low baseline levels.

However, the evidence is not uniformly strong across all respiratory conditions. While some studies suggest a protective effect, others show little or no benefit in conditions such as chronic obstructive pulmonary disease (COPD) or in populations with adequate baseline vitamin D levels. Mechanistically, vitamin D is believed to modulate the immune response, enhance production of antimicrobial peptides, and reduce inflammation in the respiratory tract. These mechanisms provide plausible biological support for its role in lung health.

Overall, while vitamin D is not a primary treatment for lung diseases, supplementation is justified in deficient individuals, and there is moderate scientific support for its role in supporting general lung and respiratory health.

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