Evidence supporting the use of: Boneset
For the health condition: Laryngitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Boneset (Eupatorium perfoliatum) is an herb traditionally used in North American folk medicine, particularly among Indigenous peoples and early European settlers. While its primary historical use was for treating fevers, influenza, and "breakbone fever" (dengue), it has also been employed in traditional herbalism as a remedy for various respiratory conditions, including laryngitis. The rationale for its use in laryngitis stems from its reputed diaphoretic (sweat-inducing), anti-inflammatory, and mild expectorant properties, which herbalists believed could help soothe inflamed mucous membranes and promote recovery from respiratory infections.

However, there is minimal scientific evidence to support the efficacy of boneset specifically for laryngitis. Modern clinical trials on boneset are virtually nonexistent, and most of the available data are anecdotal or derived from historical texts. The herb contains compounds such as sesquiterpene lactones and polysaccharides, which may have mild immunomodulatory and anti-inflammatory effects, but their direct impact on laryngitis symptoms has not been established in controlled studies.

In summary, the use of boneset for laryngitis is justified primarily by tradition, with a very low level of supporting evidence. Anyone considering boneset for this purpose should exercise caution, as the plant can be toxic at high doses and its safety profile is not well characterized.

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