Relationship: Hypothalamus and magnesium

Evidence supporting the use of: Magnesium
For the body system: Hypothalamus

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Source of validity: Scientific
Rating (out of 5): 2

Magnesium is an essential mineral involved in numerous physiological processes, including those related to the nervous and endocrine systems. While magnesium is not specifically or traditionally targeted at the hypothalamus, scientific evidence suggests that it plays a role in supporting the broader hypothalamic-pituitary-adrenal (HPA) axis, which involves the hypothalamus as a key regulatory center. Magnesium is vital for neurotransmitter synthesis, regulation of the stress response, and maintenance of circadian rhythms, all of which are coordinated by the hypothalamus (Barbagallo & Dominguez, 2013).

Research indicates that magnesium deficiency can contribute to dysregulation of the HPA axis, leading to altered stress hormone (cortisol) levels and increased susceptibility to stress-related conditions (Gröber et al., 2015). Some clinical studies have shown that magnesium supplementation may help modulate stress responses and depressive symptoms, potentially via effects on the hypothalamus and related pathways. However, direct evidence connecting magnesium supplementation to improved hypothalamic function specifically is limited, and most findings are extrapolated from broader studies of stress and neuroendocrine health.

In summary, while there is some scientific basis for magnesium’s supportive role in systems regulated by the hypothalamus, direct clinical validation for hypothalamic-specific benefits is modest. Its use is scientifically plausible but not robustly established for direct hypothalamic support.

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Evidence supporting the use of: Magnesium
For the body system: Hypothalamus

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Evidence supporting the use of: MagnesiumFor the body system: Hypothalamus

Table of Contents

Synopsis

Other ingredients that support Hypothalamus

Other body systems supported by magnesium

Products containing magnesium

Evidence supporting the use of: Magnesium
For the body system: Hypothalamus