Magnesium is an essential mineral involved in over 300 enzymatic reactions in the human body, including several that directly impact the glandular (endocrine) system. Scientifically, magnesium plays a key role in the synthesis and secretion of hormones such as insulin from the pancreas and parathyroid hormone from the parathyroid glands. Research shows that magnesium deficiency can impair insulin secretion and action, contributing to metabolic disorders like type 2 diabetes. Additionally, magnesium is necessary for the normal function of the adrenal glands, which produce hormones involved in stress response and metabolism. Some studies have indicated that magnesium supplementation can improve insulin sensitivity and may help regulate other hormone levels, though effects on all major glands are not equally well-established. While there is clear scientific evidence that magnesium is required for healthy endocrine function, direct clinical trials demonstrating broad benefits of supplementation for the entire glandular system are limited. Thus, the evidence supports magnesium's importance for specific glandular functions, but not necessarily for generalized support of the entire glandular system.