Evidence supporting the use of: Broccoli
For the body system: Glandular System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Broccoli (Brassica oleracea) is commonly associated with support for the glandular system, particularly due to its effects on hormone metabolism and detoxification pathways. Scientific interest focuses on its high content of glucosinolates, which are metabolized into biologically active compounds such as sulforaphane and indole-3-carbinol. These compounds have demonstrated the ability to modulate estrogen metabolism in the liver and influence phase II detoxification enzymes, potentially offering protective effects on hormone-sensitive tissues such as the thyroid, adrenal, and reproductive glands. Several studies have investigated the impact of broccoli and its extracts on hormone regulation, particularly in relation to estrogen and thyroid hormone pathways. For example, indole-3-carbinol supplementation has been shown to shift estrogen metabolism towards less proliferative metabolites, which may be beneficial for glandular health.

While much of the research is preclinical or based on isolated compounds rather than dietary broccoli alone, these findings provide a scientific rationale for the use of broccoli in supporting the glandular system. Clinical data in humans is limited but promising, especially regarding hormonal balance and detoxification. However, direct evidence for broad glandular system support (beyond estrogen metabolism) remains moderate, warranting a rating of 3 on the evidence scale.

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