Evidence supporting the use of: Selenium
For the body system: Female Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Selenium is an essential trace mineral with antioxidant properties, and its role in the female reproductive system has some scientific support. Studies indicate that selenium is important for maintaining proper ovarian function, follicular development, and hormone synthesis. For example, selenium-dependent enzymes such as glutathione peroxidases protect reproductive tissues from oxidative stress, which can impact fertility and pregnancy outcomes. Some research suggests that selenium deficiency may be linked to complications such as preeclampsia, miscarriage, and subfertility, though evidence is not entirely consistent. Supplementation may be beneficial in women with low selenium status, but routine use in well-nourished populations is not broadly recommended. Systematic reviews and clinical trials are limited and often involve small sample sizes or varying dosages, making it difficult to draw firm conclusions. Thus, while there is a plausible biological rationale and some observational evidence supporting selenium’s importance in female reproductive health, high-quality interventional studies are lacking. The evidence currently rates as moderate to low (2/5), justifying its use primarily in cases of deficiency or increased oxidative stress, rather than as a general supplement for all women.

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inositol
jujube
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lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
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lactobacillus reuteri
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