Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sagebrush (Artemisia tridentata) has a long history of traditional use among Native American tribes and settlers in North America for a variety of ailments, including digestive complaints such as dyspepsia (indigestion). Traditional preparations involved infusions or teas from the leaves and stems, which were consumed to relieve stomach discomfort, bloating, and digestive upset. The purported benefit is linked to the plant's bitter compounds, which are thought to stimulate digestive secretions and improve appetite, in line with the broader ethnobotanical use of bitter herbs for indigestion.

However, scientific evidence specifically supporting sagebrush's efficacy for dyspepsia is limited. While some Artemisia species (such as Artemisia absinthium, wormwood) have been investigated for digestive benefits, Artemisia tridentata has not been the subject of significant clinical study for this indication. The evidence rating of 2 reflects a predominance of traditional use with very limited scientific validation. Safety concerns also exist due to the presence of thujone and other potentially toxic compounds in some Artemisia species, which warrant caution with internal use. In summary, support for sagebrush in dyspepsia is primarily traditional, with a modest foundation in ethnobotanical practice and little direct scientific corroboration.

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