Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) has been studied in relation to diabetes, primarily because diabetes is associated with increased oxidative stress, and vitamin C is a well-known antioxidant. Some clinical studies and meta-analyses have suggested that vitamin C supplementation may help reduce fasting blood glucose, HbA1c (a marker of long-term blood sugar control), and markers of oxidative stress in people with type 2 diabetes. For example, a 2019 meta-analysis in the journal Diabetes Care found that vitamin C supplementation led to modest reductions in blood glucose and HbA1c. Proposed mechanisms include improved endothelial function, reduced lipid peroxidation, and decreased inflammation, all of which are relevant to diabetes management and its complications.

However, the overall evidence remains limited and inconsistent. Some trials show no significant benefit, and the effects observed are generally small. There is currently insufficient evidence to recommend vitamin C as a primary treatment for diabetes, and major diabetes guidelines do not advocate its use for glycemic control. Instead, vitamin C is sometimes considered as an adjunct to standard therapy, particularly for its potential role in reducing complications related to oxidative stress. In summary, while there is some scientific basis and preliminary evidence for vitamin C’s supportive role in diabetes, it is not robust enough to warrant routine use, and more high-quality research is needed.

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Products containing vitamin C

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