Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C, including its fat-soluble ester form ascorbyl palmitate, has scientific support for its role in wound healing, which encompasses the treatment of cuts. Vitamin C is essential for collagen synthesis, a key structural protein necessary for tissue repair and regeneration. Deficiency in vitamin C is associated with impaired wound healing, increased capillary fragility, and a greater risk of infection. Clinical and preclinical studies have shown that adequate vitamin C intake can enhance the healing of wounds, including skin cuts, by promoting collagen formation, modulating inflammation, and supporting immune function at the wound site.

However, most clinical research and guidelines refer to water-soluble ascorbic acid rather than ascorbyl palmitate specifically. Ascorbyl palmitate is used in some topical formulations due to its greater stability and skin penetration, but there is less direct evidence regarding its efficacy compared to ascorbic acid. Topical application of vitamin C derivatives may support cut healing, though results can vary depending on formulation and delivery. While oral vitamin C supplementation is recommended in cases of deficiency, the benefit in well-nourished individuals is less clear. Overall, scientific evidence supports vitamin C’s role in wound healing, but for ascorbyl palmitate specifically, the evidence is more limited, justifying a moderate rating.

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