Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha-galactosidase is an enzyme commonly used to help digest complex carbohydrates found in foods like beans and certain vegetables. Its primary mechanism is to break down oligosaccharides, which are otherwise fermented by gut bacteria, leading to the production of gas and, consequently, symptoms like bloating, discomfort, and flatulence. In adults, what is often referred to as "colic" may overlap with symptoms of functional gastrointestinal disorders, including excessive gas and abdominal pain. Several clinical studies have investigated the use of alpha-galactosidase for gas-related symptoms. A double-blind, placebo-controlled trial published in Digestive Diseases and Sciences (2007) found that alpha-galactosidase significantly reduced gas production and associated symptoms in adults after a high-fiber meal, compared to placebo. Other studies have corroborated these findings, noting reductions in bloating and discomfort when alpha-galactosidase is taken with meals containing complex carbohydrates. However, the evidence does not directly address "colic" per se in adults, as colic is more commonly defined in infants. The use of alpha-galactosidase is therefore based on its ability to reduce gas, a symptom that may overlap with what some adults describe as colic. While its use is scientifically validated for gas-related symptoms, specific evidence for adult colic is limited, justifying a moderate evidence rating.

More about alpha-galactosidase
More about Colic (adults)

Other ingredients used for Colic (adults)

Other health conditions supported by alpha-galactosidase

Products containing alpha-galactosidase

Nature's Sunshine Proactazyme®