Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paris polyphylla, a plant widely used in traditional Chinese medicine (TCM), has a history of application for treating various febrile illnesses, including colds with fever. Traditionally known as "Chonglou," its rhizomes have been documented in TCM texts for their heat-clearing and detoxifying properties. In classical Chinese materia medica, Paris polyphylla is listed as a remedy to "clear heat and resolve toxicity," actions which correspond to modern concepts of treating infections and inflammation, often presenting with fever. However, while animal and in vitro studies have shown that Paris polyphylla contains steroidal saponins (such as polyphyllin D) with anti-inflammatory, antipyretic, and antimicrobial effects, direct scientific studies specifically examining its effectiveness for common colds or viral fevers in humans are limited. There is no robust clinical trial evidence supporting its use for treating colds with fever. Most support for this indication comes from centuries of empirical use in East Asian medical systems and inclusion in multi-herb formulations for febrile diseases. Overall, the justification for using Paris polyphylla to treat colds with fever rests primarily on traditional usage, supported by some preliminary pharmacological data, but not by high-quality clinical evidence.

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