Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Allyl isothiocyanate (AITC) is a compound found in mustard, horseradish, and wasabi, known for its pungent aroma and taste. Traditional medicine systems, particularly in East Asia and parts of Europe, have used mustard plasters and preparations containing AITC-rich plants as folk remedies for colds, respiratory congestion, and infections. This usage is primarily based on the irritant and warming effects of AITC, which can stimulate mucous membranes and induce a sensation of clearing nasal passages, rather than on direct antiviral activity.

Scientific studies on AITC's antiviral effects are limited. Some in vitro research suggests that AITC and related isothiocyanates may have weak antimicrobial and anti-inflammatory properties, but robust clinical trials or direct evidence supporting its efficacy in treating or preventing colds in humans are lacking. Therefore, while AITC's use for colds is rooted in tradition and is still found in some folk practices, scientific validation does not currently support its use as an effective antiviral agent against cold viruses.

Overall, its use for colds is justified by tradition, with minimal scientific support for direct antiviral action. The evidence rating is low due to the lack of well-controlled human studies.

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