Glechoma hederacea (commonly known as ground ivy) has a long history of use in traditional European herbal medicine. Historically, it was administered for a variety of respiratory conditions, including coughs, bronchitis, and, less commonly, for symptoms described as "chest pain" or "tightness in the chest." These uses are documented in several ethnobotanical sources and herbals from the Middle Ages through the 19th century. The rationale for its use often related to its perceived anti-inflammatory, expectorant, and soothing properties.

However, there is minimal to no scientific evidence from modern clinical trials or pharmacological research to support the efficacy of Glechoma hederacea specifically for chest pain (angina or musculoskeletal origin). Modern research has focused on its antioxidant and mild antimicrobial properties, but not on cardiovascular health or pain relief. Therefore, while its use for chest pain is grounded in historical tradition, it lacks robust validation from scientific studies, and contemporary medical sources do not recognize it as a treatment for chest pain.

In summary, the use of Glechoma hederacea for chest pain is primarily based on traditional herbal practices, with very limited scientific support.