Evidence supporting the use of: Vitamin B12
For the health condition: Carpal Tunnel Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin B12 (cobalamin) has been investigated as a supportive treatment for Carpal Tunnel Syndrome (CTS), particularly in patients with confirmed B12 deficiency. The rationale stems from B12’s essential role in nerve health and myelin synthesis. Several small clinical studies and case reports suggest that B12 supplementation (often in its methylcobalamin form) may improve symptoms such as numbness, tingling, and pain in CTS, especially in early or mild cases. Notably, a few randomized, controlled trials have shown modest benefits in symptom relief and nerve conduction velocity improvements, but these trials often have limitations such as small sample sizes, short durations, or lack of blinding.
Mechanistically, vitamin B12 may facilitate nerve repair and reduce neuropathic symptoms, which is relevant given that CTS results from median nerve compression. However, most evidence supports B12 supplementation only in individuals who are deficient, as routine use in the general CTS population without deficiency does not have robust scientific backing.
In summary, while there is some scientific basis—mainly from small trials and mechanistic studies—for using vitamin B12 in CTS (especially in deficiency states), the overall evidence is limited and not definitive. Large, high-quality trials are lacking, so B12 is generally considered an adjunct rather than a primary therapy for CTS.
Other ingredients used for Carpal Tunnel Syndrome
rosemaryselenium
vitamin B12
vitamin B6
essential oil blend
Other health conditions supported by vitamin B12
AlcoholismAlzheimer's Disease
Anemia
Anorexia
Anxiety
Anxiety Disorders
Apathy
Autoimmune Disorders
Bell's Palsy
Birth Defects (prevention)
Burning Feet or Hands
Cancer Treatment (reducing side effects)
Canker Sores
Cardiovascular Disease
Carpal Tunnel Syndrome
Dementia
Depression
Diabetes
Endurance (lack of)
Energy (lack of)
Exercise
Fatigue
Fibromyalgia Syndrome
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Hearing Loss
Infertility
Memory and Brain Function
Mental Illness
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Nerve Damage
Nervous Exhaustion
Neuralgia and Neuritis
Numbness
Nursing
Paralysis
Pernicious Anemia
Post Partum Weakness
Pregnancy (herbs and supplements for)
Senility
Smell (loss of)
Sore or Geographic Tongue
Stress
Wasting
Products containing vitamin B12
Nature's Sunshine Love and Peas (Sugar Free Original Formula)
Nature's Sunshine AIVIA Clean Energy
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine Balanced B Complex (Vitamin B)
Nature's Sunshine Cardio Assurance
Nature's Sunshine Children's MultiVitamin & Mineral
Nature's Sunshine Liquid - Methyl Vitamin B-12 Complete
Nature's Sunshine Love and Peas (Sugar Free) NEW!
Nature's Sunshine Love and Peas
Nature's Sunshine Mega-Chel
Nature's Sunshine Methyl Combo
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Nature's Harvest
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Nutri-Calm
Nature's Sunshine Nutri-Calm
Nature's Sunshine Power Beets Pouch
Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Power Greens Pouch
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Power Meal Chocolate
Nature's Sunshine Power Meal Vanilla
Nature's Sunshine Silver Shield BioGuard Hand & Body Cream
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Energy
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine B-Complex
Nature's Sunshine VitaWave
