Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Taxifolin (also known as dihydroquercetin) is a flavonoid found in various plants, including Siberian larch and milk thistle. Its use to support capillary health is primarily based on its antioxidant and anti-inflammatory properties, which may help protect the vascular endothelium and maintain capillary integrity. Several in vitro and animal studies suggest that taxifolin can reduce oxidative stress and inhibit lipid peroxidation in blood vessels, which may, in turn, support microcirculation and capillary function. Some small human studies and clinical trials (mainly from Eastern Europe and Russia) have investigated taxifolin’s effects on vascular health, reporting improvements in microcirculation and reduced capillary fragility, especially in conditions such as chronic venous insufficiency and diabetic microangiopathies. However, rigorous, large-scale randomized controlled trials are lacking, and much of the clinical evidence is limited in quality and scope. Therefore, while there is a plausible scientific rationale and some preliminary evidence supporting the use of taxifolin for capillary health, the overall quality and quantity of evidence are limited, justifying a moderate-low rating for its efficacy in this context.

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